Writing scripts to interact with other software can be messy. What do you do when you need to interact with a software system that has an incomplete API or even no API at all? When all else fails, programmatically controlling your keyboard, mouse, and web browser lets you automate processes that would otherwise require tedious typing and clicking. This talk is an introduction to Selenium and PyAutoGUI modules for Python. Web scraping and GUI automation frameworks have an intimidating reputation for a steep learning curve. While they do have many sophisticated features, the basics that most folks will ever need can be covered in a single presentation. This presentation has multiple live demos to showcase these modules straight from the interactive shell.