Machine Learning at the Edge of Scale and Speed: Nanosecond Inference at the CERN Large Hadron Collider

QCon London 2026

Session AI/ML

Machine Learning at the Edge of Scale and Speed: Nanosecond Inference at the CERN Large Hadron Collider

Wednesday Mar 18 / 10:35AM GMT, Windsor (5th Fl.) at The QEII Centre, London

Abstract

The CERN Large Hadron Collider (LHC) produces O(10,000) exabytes of raw data annually from high-energy proton collisions. Handling this volume under strict compute and storage limits requires real-time event filtering capable of processing millions of collisions per second. A multi-tier architecture of ASICs, FPGAs, CPUs, and GPUs reconstructs and analyzes events, rejecting >98% of data within microseconds.

With the transition to the High-Luminosity Large Hadron Collider (HL-LHC), the first trigger stage, located in radiation-shielded caverns ~100 m underground, must handle data rates approaching ~5% of global internet traffic and significantly increased event complexity. Maintaining physics sensitivity therefore requires highly efficient machine-learning algorithms optimized for real-time inference with extreme throughput and ultra-low latency.

In this talk, we will discuss emerging techniques for low-power, low-latency inference, including hardware-aware model design, quantization, sparsity, and hardware-software co-design. Using examples from particle physics and other domains, we will show how real-time machine learning is both a practical necessity and a powerful tool for scientific discovery.

Topics

AI/ML systems real-time fpga asics
76% senior dev or higher
1:11 speaker ratio
60+ practitioners

QCon London 2026 is a three day conference for senior software engineers, architects and team leads. An international program committee of working engineers selects every session. Patterns and practices, not products and pitches.

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Wednesday 18 March

10:35 Windsor (5th Fl.) Session AI/ML Machine Learning at the Edge of Scale and Speed: Nanosecond Inference at the CERN Large Hadron Collider Thea Klaeboe Aarrestad Particle Physics and Real-Time ML @CERN @ETH Zürich 11:45 Windsor (5th Fl.) Session Data Systems Vector Search on Columnar Storage Peter Boncz Professor @CWI, Co-Creator of MonetDB, VectorWise and MotherDuck, Database Systems Researcher, and Entrepreneur 13:35 Mountbatten (6th Fl.) Session architecture Not Just I/O: Using Async/Await for Computational Scheduling Orson Peters Senior Engineer of Query Execution @Polars, (Co-)Author of Stdlib Sort in Rust & Go 14:45 Mountbatten (6th Fl.) Session Data Management Looking Under the Hood: Data Processing Systems Performance Tricks (and How to Apply Them to Your Code) Holger Pirk Associate Professor for Data Management Systems at Imperial College London and Avid Runner — Minimizing Cache Misses, Thread Divergence and Aerobic Decoupling 15:55 Windsor (5th Fl.) Session compilers Automatically Retrofitting JIT Compilers Laurence Tratt Shopify / Royal Academy of Engineering Research Chair in Language Engineering @King's College London